Chondrogenic Potential of Dental-Derived Mesenchymal Stromal Cells
نویسندگان
چکیده
The field of tissue engineering has revolutionized the world in organ and regeneration. With robust research among regenerative medicine experts researchers, plausibility regenerating cartilage come into limelight. For engineering, orthopedic surgeons orthobiologists use mesenchymal stromal cells (MSCs) various origins along with cytokines, growth factors, scaffolds. least utilized MSCs are dental origin, which richest sources progenitor cells. There is a paradigm shift towards utilization source chondrogenesis Dental-derived possess similar phenotypes genotypes like other specific markers such as dentin matrix acidic phosphoprotein (DMP) -1, sialophosphoprotein (DSPP), alkaline phosphatase (ALP), osteopontin (OPN), bone sialoprotein (BSP), STRO-1. Concerning chondrogenicity, there literature marginal dental-derived MSCs. Various studies provide evidence for in-vitro in-vivo by evidence, clinical trials must be taken up to support or refute tissues This article highlights significance
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ژورنال
عنوان ژورنال: Osteology
سال: 2021
ISSN: ['2673-4036']
DOI: https://doi.org/10.3390/osteology1030016